Edge effects treatment for crystals

ABSTRACT

A scintillator, for use in a radiation imaging device, has a light-emitting face, a radiation receiving face, and a perimeter extending between the light-emitting face and the radiation receiving face, the perimeter including an edge, the edge having an edge thickness. The scintillator emits scintillation light from the light emitting face in response to radiation incident on the radiation receiving face. The scintillator has one or more light guides formed therein with guides within a peripheral region being deeper than guides in a non-peripheral region.

REFERENCE TO RELATED APPLICATIONS

This application is a continuation-in-part of U.S. patent applicationSer. No. 10/993,012, filed Nov. 19, 2004, which claims priority of U.S.Provisional Patent Application Ser. No. 60/523,765 filed Nov. 20, 2003,the entire content of both of which are incorporated herein byreference.

FIELD OF THE INVENTION

The invention relates to improved apparatus and methods relating toreduction or elimination of edge effects in optical elements, forexample, scintillators.

BACKGROUND OF THE INVENTION

A scintillation material, or scintillator, produces light in response toincident radiation, typically ionizing radiation such as gamma rays orx-rays. Such a material can be a crystal such as thallium-doped sodiumiodide, NaI(T1), or a non-crystalline material such as a plastic.

Radiation detectors using scintillators include gamma cameras, x-raydetectors, and other radiation imaging or sensing devices. Thescintillator generally has a radiation receiving face on which radiationsuch as gamma rays are incident. The scintillator has a light outputface from which light emerges in response to incident radiation, andalso an outside edge. For example, a disk-shaped scintillator would havea cylindrical edge surface. An optical window, such as glass, istypically bonded to the light output face of the scintillator. An arrayof light sensors, such as photomultiplier tubes, receive scintillationlight emitted from the light output face of the scintillator, andtransmitted through the window to the detectors. A plastic “light pipe”is sometimes interposed between the window and the light sensors.

The light is generated within the scintillator as pulses (also termedscintillation events). The positions of light pulses generated withinthe scintillator are used in imaging applications, such as SPECT (singlephoton emission tomography) and PET (positron emission tomography)imaging. Such uses may be generally referred to as scintillationimaging.

A problem in scintillation imaging is that reflections from the edge ofthe scintillator will reduce the measured positional accuracy of imagingdata, particularly for scintillation events occurring close to the edgeof the scintillator. Light from scintillation events occurring near anedge will be reflected from that edge, causing a serious reduction inability to accurately determine the position of such events. Inpractice, a dead zone may exist around a peripheral region, proximate tothe edge of the scintillator or window, from which meaningful positionaldata cannot be collected. This dead zone or “edge effect” reduces theeffective usable portion of the scintillator. In addition, the presenceof this unusable region at the periphery of the detector prevents thedetector from being positioned optimally in many medical applications,for example breast and brain scintigraphy. The increase in detector bulkcaused by the wasted portion of the detector may also make it difficultto position the detector sufficiently close to the patient inapplications such as heart scintigraphy and many forms of SPECT.

In some detector designs, it is desirable to have more than onescintillator element in close proximity to another. In this situation,the junctions between elements tend to act as reflecting edges causingan unusable dead zone of edge effect on each side of the junctions.

This problem is well recognized in the field. For example, a previousattempt to solve this problem is described in U.S. Patent ApplicationPublication 2003/0034455 to Schreiner et al., which suggests segmentingthe scintillator into a number of triangular segments. However, suchsegmentation adds to the cost of a device, is difficult to fabricate andmay cause problems if the scintillator absorbs moisture from the air.For example, it is well known that sodium iodide should be protectedfrom atmospheric moisture.

Another attempted solution is described by U.S. Pat. No. 4,284,891 toPergale et al., which suggests providing a diffused light reflectoraround the periphery of the optical window. However, it can be difficultto provide a true diffused reflector, as reflection properties of manymaterials and the crystal edge will change with time and environmentalconditions. In addition, such diffused edge treatments have been foundin practice to provide an unsatisfactory degree of improvement to theproblem.

Hence, there is a need for improved scintillators and radiationdetectors which reduce or eliminate the undesirable effects of edgereflection.

SUMMARY OF THE INVENTION

Methods and apparatus are provided to reduce edge effects, such as lossof positional accuracy due to edge reflection, in optical elements suchas scintillators. For example, one or more light guides can be providedin a peripheral region of a scintillator or optical window close to anedge.

A radiation detector according to an example of the present inventioncomprises a scintillator having a light-emitting face, a radiationreceiving face, and a perimeter extending between the light-emittingface and the radiation receiving face, the perimeter including an edge.The scintillator emits scintillation light from the light emitting facein response to radiation incident on the radiation receiving face. Oneor more light guides are formed within a peripheral region proximate tothe edge, a light guide redirecting a portion of scintillation lightbefore it emerges from the light emitting face. The radiation detectormay further comprise a number of light sensors receiving scintillationlight from the scintillator.

Light guides provided within the peripheral region can improve thepositional accuracy of the radiation detector. There may be a pluralityof spaced apart light guides formed only within the peripheral region.The light guides may include grooves having a groove depth whichdecreases as the distance of the groove from the edge increases.

The light emitting face of the scintillator may have a non-peripheralregion, such as a central region, in which there are no light guides.Depending on the application, the non-peripheral region may be larger,sometimes substantially larger, than the peripheral region.

The peripheral region is a region within a certain distance of the edge.The distance may be some multiple of an edge thickness, such as lessthan ten times, for example within eight times the edge thickness of theedge. The distance may also be the approximate diameter of a lightsensor.

A light guide may comprise a groove formed in the light emitting faceand/or the radiation receiving face of a scintillator. In otherexamples, light guides may be provided in a window between ascintillator and a detector or detectors. A light guide may comprise agroove, reflecting film, an interface or other boundary between tworegions of different refractive indices, or other structure providing aninternal reflection or refraction of light within the scintillator. Thelight guide can be substantially parallel to the edge.

Another example of an improved radiation detector comprises ascintillator, an array of sensors in optical communication with a lightemitting face of the scintillator, a window between the scintillator andthe array of light sensors, the scintillator and/or the window havingone or more grooves formed in a face thereof. The grooves may be formedonly within a peripheral region of the scintillator and/or window.

In examples discussed below, the term “crystal” is often used forconvenience to refer to a scintillation material. However, any examplediscussed here equally applies to non-crystalline scintillators. Themethods and apparatus described can also be adapted for use in otheroptical elements, as will be clear to those skilled in the optical arts.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 shows a side view of a pair of crystals, each having a number ofgrooves cut in respective peripheral regions proximate to crystal edges;

FIG. 2 shows a side view of a crystal, showing grooves cut in the lightoutput face of the crystal within a peripheral region proximate to thecrystal edge;

FIG. 3 is a side view of a pair of crystals, each having grooves cut ina peripheral region of the radiation receiving face;

FIGS. 4A and 4B show top views of a crystal;

FIG. 5 shows a side view of a crystal, having both a window and anoptical transmission element, the latter having grooves cut in the lowerface;

FIG. 6 is a side view of a radiation detector, including a crystal and awindow having grooves cut in the lower face of the window;

FIG. 7 is a side view of a radiation detector, having both a window andan optical transmission element, each having grooves;

FIG. 8 is a side view of a radiation detector, having grooves in boththe crystal and the window;

FIG. 9 is a side view of a radiation detector having grooves in thecrystal and the window, the grooves not being in register;

FIG. 10 shows a radiation detector, having grooves in the upper andlower faces of both the crystal and window;

FIG. 11 shows a radiation detector, the window/light pipe having anupper surface shaped so as to direct light to a plurality of sensors,the window also having grooves in a peripheral region;

FIG. 12 shows a curved crystal having grooves in a peripheral region;

FIG. 13 shows a circular crystal having circular grooves;

FIG. 14 shows a radiation detector configuration including a computerand display;

FIG. 15 shows a radiation detector having two crystals and a metalhousing;

FIG. 16 shows a cross section of a scintillation crystal with lightguides formed in the peripheral and non-peripheral regions; and

FIG. 17 shows a cross section of another scintillation crystal withlight guides formed in the peripheral and non-peripheral regions.

DETAILED DESCRIPTION OF THE INVENTION

In examples discussed below, the term “crystal” is used for convenienceto refer to a scintillation material. However, examples discussed hereapply equally to non-crystalline scintillators. Also, in examplesdiscussed below, light guides are provided by grooves cut into one ormore surface of the crystal (or associated window). As discussed in moredetail below, other forms of light guide can also be used, for example,reflective films.

FIG. 1 shows a portion of a first crystal 10, a portion of a secondcrystal 12, a crystal gap 14 between the two crystals, a plurality ofsensors such as sensor 16, a plurality of grooves in the light emittingface of each crystal, such as grooves 18 a-18 d, a first crystal edge20, and a second crystal edge 22.

As drawn, the lower surface of the crystal 10 is the radiation receivingface, and the upper surface of the crystal is the light emitting face.This convention will be followed (for convenience only) through thevarious figure descriptions.

The light emitting face and radiation receiving face can be generallyparallel and coextensive, and interconnected by a perimeter, theperimeter defining an edge. The crystal can be in the form of a cuboid,having a length, width, and thickness, the thickness being the edgethickness. The thickness may be substantially less than the lengthand/or width of the crystal.

Sensors may be in different positions from those shown. A sensor may,for example, span the gap between two crystals. Sensors may be providedin a linear or two-dimensional array, or other configuration. Scanningimaging methods may also be used.

FIG. 2 shows another view of crystal 10. The star symbol at 28represents a pulse of scintillation light (a scintillation event)produced by radiation interacting with the crystal. For convenience, theterm “scintillation light” will often be abbreviated to “tight”. Thezigzag arrow labeled L represents a possible path of light out of thecrystal. For convenience, not all grooves are shown.

Light will tend to propagate in all directions within the crystal 10from the scintillation event (the production of a pulse of light).However, the arrows show the groove 18 a and crystal edge 20 operatingcooperatively to provide a light guiding effect, whereby light isreflected from the crystal edge and from the inner surface of the grooveso as to take a path remaining proximate to the edge, and to emerge fromthe light emitting face within a portion of the light emitting facebetween the groove and the crystal edge. Hence, the groove 18 a and thecrystal edge 20 provide partial optical conferment, or a waveguideeffect.

FIG. 3 shows a first crystal 40, a second crystal 42, a separation gap44, grooves such as groove 46 in the radiation receiving face of eachcrystal, and a plurality of sensors such as sensor 48. The sensors arein optical communication with the upper face, or light emitting face, ofeach crystal. This figure illustrates that grooves may be provided inthe radiation receiving face of the crystal, as well as or instead ofgrooves in the light emitting face.

FIG. 4A shows a top view of a crystal, showing a rectangular lightemitting face, having a surface (such as the light emitting face) 50,and a plurality of grooves such as 56 and 58 around the periphery of thecrystal, proximate to the edge. The edge is shown as rectangular,including sides 52 and 54. The grooves may have equal depth, or in otherexamples the groove depth is greatest for the groove closest to the edge(groove 58), and shallowest for the groove furthest for the edge (groove56). The depth of grooves can be correlated with the distance from theedge, for example inversely proportional to the distance, as discussedin more detail below.

The crystal may also have a rectangular cross section, so as to have acuboid form. The orthogonal edge regions of the crystal, as illustratedin FIG. 4A, may be designated as sides or edges, as preferred. Analogousgroove patterns may be formed in one or more faces of the crystal and/orwindow.

FIG. 4B shows a top view of another example, in which grooves formed inthe surface 59 form a cross-hatched pattern in the comers. Other detailsmay be the same as discussed above in relation to FIG. 4A.

FIG. 5 shows a side view of a radiation detector comprising aradiation-side optical transmission element 60, a crystal 62, a window64, an optical matching medium 66, a plurality of sensors such as sensor68, and a plurality of grooves such as 70 and 72. In this example thegrooves are formed in the upper side of the optical transmission element60, proximate to the radiation receiving face of the crystal 62.

In another example which may appear similar to that illustrated in FIG.5, the radiation detector comprises a crystal and lower and upperoptical transmission elements or window layers supported by the lightemitting face of the crystal. The grooves can be formed in the lightemitting face of the crystal.

FIG. 6 represents a side view of a radiation detector, comprising acrystal 80, a window 82, a plurality of sensors such as sensor 84, and aplurality of grooves such as grooves 86 and 88. In this example, thegrooves are formed in the lower side of the window, the side of thewindow proximate to the light emitting face of the crystal. It should berecalled that the crystal and the window, both typically beingtransparent, may be considered as a single optical element., i.e.together they form a continuous medium for transmission of light. Thus,placement of groves in the window provides a reduction in edge effect inthe same manner, although to a lesser extent, as do grooves in thecrystal itself. It should also be appreciated that light reflectionsoccur from both the edge of the crystal and from the edge of the window.Reflections from the edge of the window may further degrade spatialaccuracy beyond the effects of edge reflections in the crystal itself.An existing radiation detector may be improved by the simple process ofreplacing the existing window with a window having a plurality ofgrooves within the side of the window proximate to the crystal. Inanother example, the grooves may be formed in the upper face of thewindow, the face most distant from the crystal.

FIG. 7 shows a radiation detector comprising a radiation side window oroptical transmission element 100, a crystal 102, a window 104, a sensor106, grooves such as 108 and 110 in the radiation-side window proximateto the radiation receiving face of the crystal, and grooves such as 112and 114 in the lower surface of the window proximate to the lightemitting face of the crystal.

In another example, which may appear similar to that illustrated in FIG.7, a radiation detector comprises a crystal, a lower window, and anupper window. In this example, grooves are provided within the crystaland within one or two window layers transmitting light from the crystalto the sensor,

FIG. 8 illustrates a radiation detector comprising a crystal 120, awindow 122, and a sensor 124, with grooves such as 128 provided in thelower surface of the window. Grooves such as 126 are provided in theupper surface of the crystal. In this example the grooves in the crystaland the grooves in the window are substantially in register.

FIG. 9 shows a radiation detector comprising a crystal 140, a window142, a sensor 144, grooves such as 146 in the upper surface of thecrystal, and grooves such as 148 in the lower surface of the window. Inthis example the grooves in the crystal and grooves in the window aresubstantially out of register.

FIG. 10 shows a radiation detector comprising a crystal 160, a window162, a sensor 164, grooves such as 166 in the lower face of the crystal,grooves such as 168 in the upper surface of the crystal, grooves such as170 in the lower surface of the window, and grooves such as 172 in theupper surface of the window.

FIG. 11 shows a radiation detector comprising a crystal 180, a window182, and a sensor 184, the window having an upper surface topography 186designed so as to direct light towards the light sensitive regions ofthe sensors. Grooves such as 188 are shown provided in the lower surfaceof the window, but alternatively or additionally could be in eithersurface of the crystal or the upper surface of the window.

A series of triangular indentations 190 are provided in the uppersurface of the window so as to prevent light being lost to dead spaceswithin or between the sensors, which would otherwise not be detectedAlternatively, structure 182 may be composed of two elements, a windowproximate to the crystal and a “light pipe” interposed between thewindow and the light sensors. Other surface topographies can be used, asdiscussed further below.

FIG. 12 shows a curved (arcuate) crystal 200 having grooves 202 within aperipheral region, proximate to one edge of the crystal. In this examplethe grooves are substantially radial extending from the lower surface ofthe crystal towards the interior.

FIG. 13 is a top view of a circular crystal 220, having a circular edge222, and grooves 224 and 226 within a peripheral region proximate to theedge.

FIG. 14 shows a radiation detector comprising a radiation source 240, acrystal 242, a window 244, a light sensor array 246, a computer 248, adisplay device 250, a data port (for example, a data input device) 252,and an analysis circuit 254. A computer program running on the computer248 can be used to extract position information provided by the lightsensor array. Algorithms may be provided to provide edge corrections,depth corrections and other corrections as well known in the art. Theanalysis circuit may comprise noise reduction circuitry, and the like,and may be integrated with the computer into a single device. Theradiation source may be a mammal under diagnosis.

FIG. 15 shows a side view cross section of a radiation detectorcomprising a housing 260, a first crystal 262, a second crystal 264,substantially in abutment to the first crystal, and a window 266. Thehousing 260 can be a metal such as aluminum, and may provide protectionof the crystal from atmospheric moisture or other sources ofdegradation. A detector array 270 includes a plurality of light sensorssuch as 272 as well as associated positioning circuitry. Grooves such as268 are shown within peripheral regions of each crystal so as to reduceedge effects from reflections, and improve the accuracy of positionaldata provided by the sensor array 272 provided above the window.

In other examples, two windows can be provided in register with thecrystals, and grooves provided in the windows close to the ends.

Light Guides (Grooves)

The term “light guide” can be used to refer to any structures that maybe provided within a crystal to provide internal redirection of light.The light guide may be a groove (such as a cut in the surface of thecrystal), and the term “groove” is used elsewhere for convenience torepresent light guides. The term groove includes structures such ascuts, slots, and the like.

A light guide may include a groove, an interface between media ofsubstantially different refractive indices, a reflective film, bubbles,defects, crystal defects such as crystal grain boundaries, fracturefilms, or other structure or components that provide redirection oflight within the crystal before the light emerges from the lightemitting surface. Light guides may also comprise embedded fibers,plastic or metal films, or other materials.

A groove can be air filled, or filled with fill material such as aliquid, plastic, glass, reflective film (such as a plastic or metalfilm), multilayer reflective film, fibers, spheroids (for example,forming a photonic band-gap reflector), interferometric structure, inertgas, vacuum (if the scintillator is in a sealed housing), or othermaterial.

A light guide can be substantially parallel to a proximate edge region,and/or substantially normal to a surface in which it is formed, ornearby surface. A plurality of spaced apart light guides can be formedwithin a peripheral region. The depth or other extent of each lightguide can be inversely correlated with the distance of the light guidefrom the edge (the distance being measured between the light guide andthe most proximate region of the edge). The light guides may not extendentirely to any surface of the crystal or window, but may instead bedisposed inside the volume of the crystal or window.

In other examples, light guides can be provided across the fill extentof a surface, not just in a peripheral region. As for peripheral lightguides, the depth (or analogous extent) of the light guide can beinversely correlated with the distance from the nearest edge (less whenfurther from the edge, the relationship can be linear or nonlinear). Inone example, peripheral light guides have a depth that is inverselycorrelated with the distance from the nearest edge, and light guides ina middle region of the surface can all have an equal depth. This exampleis illustrated in FIG. 16, where the body of scintillation material isillustrated at 300. A plurality of light guides 302 are formed in thebody 300. Peripheral region 304 is illustrated between outboard edge 306and line P-P. An opposing peripheral region is illustrated at 308. Thelight guides in the peripheral region all have depths greater than thedepths of the guides in the non-peripheral region 310. In this example,the light guides in the non-peripheral region all have the same depth.In another example, illustrated in FIG. 17, the light guide depths areinversely correlated with the distance from an edge, across the entiresurface.

A light guide can provide partial optical confinement of scintillationlight between the light guide and either another light guide or an edge.The partial optical confinement can improve the positional accuracy of aradiation detector using the scintillator.

If the scintillator has an elongated form having a uniformcross-section, having a first end and a second end, light guides can beformed in peripheral regions proximate to one or both ends.

The number of light guides proximate to an edge may be a number withinthe range 1-20 (inclusive), such as in the range 1-10 (inclusive), forexample, one, two, three, four, five, six, seven, eight, nine, or ten.Example scintillators were made with 5-7 grooves, which were found toImprove positional accuracy and dramatically reduce the edge effect deadzone near crystal edges.

Groove spacing may be regular (equal spacing), or non-equally spaced.Graduations in groove depth can be linear or non-linear with distancefrom the edge, or all grooves can be the same depth.

It is preferred that the light guide depth near the edges be graduated.Equal-depth grooves or light guides in a periphery region may bebeneficial for some applications, but they tend to produce a zone ofedge effect inside the innermost groove, i.e. the innermost groove actslike an edge. A groove extending only partway through the crystal doesproduce less of an edge effect than a full edge however, and istherefore somewhat useful.

The preferred embodiment, however, is the progressively graduatedgrooves or light guides becoming shallower as one moves inward from theedge. Since the grooves are deeper on one side of the “waveguide” thanthe other, they limit light spread more in one direction than the other.This produces a gradual effect rather than a sharp edge, thuseliminating all or more of the dead zone. This is due to a “one-way”diffusion aspect of the graduated depth arrangement. This can be mosteasily explained by reference to one of the simplest arrangements of thepresent invention, where grooves or light guides are provided in thelight emission side of the crystal only. Light can diffuse beyond theconfines of the “waveguide” at the bottom. Light that exits a waveguideat the bottom can go either toward the edge or away from the edge. Sincethe open path (space between bottom of light guide and bottom surface ofcrystal) towards the edge is smaller than the open path away from theedge, light is more likely to diffuse away from the edge. This “pushes”the emitted light away from the edge. The intensity of light reachingthe light sensors, instead of being a bell shaped curve is now skewed,with a wider spread away from the edge. This “pushing” of the lightemission profile away from the edge also happens for light reaching thebottom of the next waveguide further from the edge. This includes bothlight that traveled down that waveguide plus light that traveled to thatpoint from the adjacent waveguides. This causes the emission profile tobe skewed even further away from the edge. This skewing effect becomesless and less, however, as one looks at waveguides further and furtherfrom the edge. This is because, proportionally, the relative openingstoward and away from the edge become more and more equal. For theinnermost waveguide, the chance of a light photon going to the right isalmost as great as its chance of going to the left. Thus, the emittedlight is pushed away from the edge effect dead zone, but the degree towhich it is pushed away gets less and less, the further one moves fromthe edge. This causes the edge effect to be blurred out and spread overa wide region.

In addition to the above, the resolution enhancing effects of the lightgrooves both improve resolution and mitigate the resolution reducingeffects of “smearing” the edge reflections over the whole peripheralregion.

The positional accuracy of an imaging device can be increased byproviding more closely spaced grooves. The groove spacing may be, forexample, a fraction of a sensor diameter, such as a spacing within therange 0.01-1 times the sensor diameter, such as in the range 0.05-0.5 ofthe sensor diameter. The groove spacing may also be a fraction of theedge thickness, such as in the range 0.01-0.5 times the edge thickness.

If the grooves have variable groove depth, such as groove depthsinversely correlated with distance from the edge, in some examples theshallowest groove may be approximately 1 mm, and the deepest grooveapproximately equal to half the edge thickness. In some examples, thegrooves may be curved.

Peripheral Region

The peripheral region can be defined in terms of the sensor width, for aradiation detector including a plurality of sensors. The sensor widthmay be for example, the outer diameter of a sensor, or the averagespacing distance of sensors. The peripheral region can be defined as aregion proximate to the edge of the scintillator, and not more than adistance approximately equal to the sensor width from the edge.Alternatively, the peripheral region can be defined as a regionproximate to the edge of the scintillator, and not more than a distanceapproximately equal to the half the sensor width from the edge. If thesensor is a photomultiplier tube, the sensor width may be termed thetube width.

The peripheral region can also be defined in terms of a fraction of theoverall dimensions of a surface. For example, the peripheral region of acrystal or window may be a region proximate to the edge, and not morethan a certain fraction of the distance from the center to that edge.The certain fraction may be, for example, 5 percent, 10 percent, 15percent, or 20 percent.

The peripheral region can also be defined as a region proximate to theedge, and not more than six to eight times the thickness of the slabfrom the edge. Alternatively, the region may be less, such as 3-4 timesthe thickness. The peripheral region can also be defined as a regionproximate to the edge, and not more than approximately the thicknessfrom the edge. In one example, the crystal has a thickness of ¼″ to ⅜″,the phototubes have a diameter of 2″-3″, and the peripheral region is1″-1.5″.

In one example, a radiation detector can include a scintillator in theform of a cuboid slab having a slab length, a slab width, and a slabthickness (equal to an edge thickness), with the slab length and slabwidth both being substantially greater than the slab thickness. Theperipheral region, for some examples, may be an outer region of the slabwithin approximately three to eight times or approximately equal to theedge thickness from the edge.

Manufacture of Light Guides

Light guides (such as grooves) may be formed by a variety of mechanical,chemical, optical, ultrasonic, or other means. For example, a saw can beused to cut grooves in one or more surfaces of a crystal. Grooves mayalso be formed by a high pressure jet of fluid. It is known that sodiumiodide, a common crystal material, is soluble in water. In this case anon-aqueous fluid could be used, such as an oil, supercritical carbondioxide, or other fluid. Water can also be used, and the surface driedquickly after jet cutting. A high pressure gas jet such as carbondioxide or nitrogen can also be used to provide grooves in a surface.

A laser can be used to ablate or otherwise provide grooves or cuts inthe surface of a crystal. For laser cutting, it is advantageous to use adifferent wavelength from that of the light produced by radiation withinthe crystal, as the crystal will presumably be substantially transparentto that wavelength; for example, x-ray, U-V or IR wavelengths may beused if the scintillation light is in the visible region. The crystalmay include additives so as to absorb laser radiation within apredetermined range of wavelengths to facilitate crystal processing.

Inclusions, bubbles, or defects may also be used to provide redirectionof light within the crystal. For example a laser focused within the bulkof the crystal may be used to vaporize part of the crystal so as toprovide an air bubble. Such defects may be provided in a regular arrayor pattern so as to provide the desired light guiding effect.

Bubbles may also be injected into the molten medium from which thecrystal is formed. The crystal may also include other materials having asubstantially different refractive index so as to provide refractivelight guiding. Light guides, such as grooves, may also be formed bymolding (for example of plastic or molten materials, for example duringcrystal growth), stamping, drilling, other mechanical processes,chemical etching, ion bombardment, electron beams, atomic beams,lithographic processes, and the like.

Crystal Geometry

A crystal may have a cuboid shape, having a light emitting face, anopposed radiation receiving face, and a rectangular edge (includingfirst and second opposed ends, and first and second opposed sides). Anypair of opposed ends may be alternatively designated as sides, or viceversa.

The crystal has a crystal thickness, defined as the distance between thelight emitting face and opposed radiation receiving face. The two facesmay be parallel, providing a uniform thickness.

The light emitting face extends between the first and second ends, andbetween the first and second sides. Similarly, the radiation receivingface, opposed to the light emitting face, can be substantially parallelto the light emitting face and also extending between the first andsecond ends.

In other examples the crystal may be curved (actuate), for exampleeither being formed initially in a curved or actuate shape, bent aftercrystal formation, or bent after heating or other softening process. Thebending process may take place during heating of a crystal. The curvemay be in a single plane, or may be in three dimensions so as toprovide, for example, a spherical section.

Grooves may be formed generally normal to either the light emitting faceor radiation receiving face. Grooves may be parallel to the portion ofthe edge to which they are proximate, for example parallel to the firstor second end.

The grooves may be equally spaced, or provided at irregular intervals.The depth of the groove within the crystal, the depth being defined asthe distance between the face into which the groove is cut and thedistal end of the groove, can be correlated from the distance of thegroove from the nearest end. For example, the correlation may be linear,exponential, quadratic, or other mathematical form.

Hence, an improved radiation detector includes a scintillator having theform of a slab, the radiation receiving face and the light emitting facebeing generally parallel, the slab having a slab width and a slabthickness, the slab thickness being equal to the edge thickness, theslab width being substantially greater than the edge thickness, thescintillator having a peripheral region, the peripheral region beingproximate to the edge, the scintillator including one or more lightguides formed only within the peripheral region. A plurality of groovesare formed in the peripheral region, the grooves acting as light guides,the depth of each groove being inversely correlated (such as inverselyproportional) to a distance of the groove from the edge.

The crystal and window thicknesses can be approximately the same. Thecrystal and window thicknesses can be different relative thicknessesthan shown in the Figures. A typical crystal (or edge) thickness may bein the range 0.125-3 inches, such as in the range 0.25 inches-0.5inches, such as in the range of 0.25 to 0.375 inches. In some examples,the deepest groove can less than or equal to one half the edgethickness.

Some crystals, especially for PET work, may be substantially thicker,such as having a thickness greater than a width. The present inventionmay be used with these thicker crystals as well.

Scintillation Materials

Scintillation materials may comprise halides (such as sodium iodide,cesium iodide), oxides (such as bismuth germinate (BGO), cadmiumtungstate, gadolinium orthosilicate (GSO), cerium doped yttriumorthosilicate (YSO), cerium doped lutetium orthosilicate (LSO), and thelike), other inorganic materials (for example, as inorganic crystals),organic crystals, other organic materials, and other materials.Scintillation materials may include an activator and a host material, inwhich the activator is dispersed or otherwise disposed. The activatormay be a transition metal, such as a rare earth metal. Scintillationmaterials can be crystalline or non-crystalline. Non-crystallinescintillation materials may comprise, for example, polymers, glasses,and other materials providing light in response to incident radiation.

In this specification, examples are provided referring to crystals,where the term crystal is used to refer to the scintillation material,such as a scintillation crystal. However, the methods and apparatusdescribed herein can be used with any scintillation material, such ascrystal or non-crystal scintillators, and also with other materials thatproduce light in response to non-ionizing radiation, such as fluorescentmaterials, or other optical elements in which edge reflections are aproblem.

Windows

A window generally comprises a material substantially transparent toscintillation light. For example, a window may be bonded to, abutting,or proximate to the light output face of a crystal. The window canprovide protection of the crystal from degradation, for example byprotecting from scratches, moisture, fracture, and the like.

The window may be formed from any material substantially transparent tothe scintillation light. Examples include glass, polymers (such asacrylic polymers, for example PMMA), transparent oxides, or othermaterials.

The topography of the upper surface of the window may include triangularindentations, pyramids, truncated pyramids, cones of conic sections suchas frustoconical shapes, lenses, microlens arrays, Fresnel lenspatterns, or other surface features operable to guide light towardslight sensitive regions of the sensor. Equivalently, a window may beslab shaped, with a separate layer in optical communication with theupper surface providing light guiding. In the field of nuclear medicine,this separate layer is often referred to as the “light pipe”.

The window may have a thickness in the range 0.1-0.375 inches, thoughthis is not limiting. If the window has a surface topography within theperipheral region, for example to direct light to sensors, grooves canbe formed through such features. The grooves may be normal to theaverage plane of the upper surface, may be parallel to a proximate edge,or otherwise provided.

Light guides (such as grooves) can be provided in the window material,so as to reduce edge effects due to reflections from the edge of thewindow. The grooves in the window can be in addition to, or instead of,grooves in the crystal.

Analogous geometries can be used to the crystal examples describedpreviously, and vice versa. Grooves in the crystal can be combined withgrooves in the window.

The window may overhang the crystal edges, which may reduce edge effectsdue to the crystal, and the addition of grooves in the window mayfurther reduce edge effects due to reflections from the window edges.

Provision of grooves in the window can advantageously increasepositional accuracy of an imaging device. The improvement may not be asgreat as grooves formed in a crystal. However, even if it is notpossible to replace the crystal of an imaging device, the positionalaccuracy of the device can be improved by replacing a non-grooved windowwith a grooved window.

Housing

If a humidity sensitive scintillator crystal such as sodium iodide isused, a housing may be necessary to protect the crystal from the effectsof atmospheric moisture. A housing may also be provided to increaserobustness, hold together multiple crystals, or other purpose. Thehousing preferably does not substantially attenuate the incidentradiation, but need not be transparent to scintillation light. Examplehousing materials include aluminum, other metals, plastics and the like.

Reflectors

To prevent light escaping from the radiation receiving face of thecrystal, and therefore not being detected by the sensor array,reflectors may be provided. For example, a reflector may be provided bythe inner reflective surface of an aluminum housing. A reflective film,such as a separate metal film or photonic band gap layer, may also beprovided. For example, a reflective metal film may be evaporated ontothe radiation receiving surface of a crystal. Interferometric reflectorsand diffuse reflectors may also be used. Diffuse reflectors includepolymer films (such as Teflon, porous Teflon, polyethylene, and thelike), inorganic materials such as substantially white crystal layers,inorganic material doped polymers, and the like.

Reflectors may also be provided at the edges of the crystal and/orwindows. The edge of the crystal will typically reflect scintillationlight. However, additional reflector(s) can be provided.

Generally, the groove spacing will be much greater than the wavelengthof scintillation light, so as not to provide a photonic band gap (PBG)effect or other interference effect. However, PBG regions or otherreflective films can be provided at the edges or radiation receivingface of the crystal, if required. This can be in addition to any groovesor other light guides provided.

Absorbers may also be provided to reduce unwanted stray reflection fromany surface, for example around the apertures of the sensors.

Sensors and Circuitry

Sensors which may be used include photomultiplier tubes CPMT), solidstate sensors such as avalanche photodiodes, or other light sensitivedevices. The sensors can be provided in a linear or two-dimensionalarray. Positional information of scintillation events can be determinedfrom sensor signals.

After grooves are cut in a crystal, there may be a sensitivityreduction, due to the reduced local volume of crystal, requiring anattenuation correction. A linearity correction can also be provided tocorrect for any warping or spatial distortion of the image.

Amplifiers may be provided to improve the signal-to-noise ratio of thesensor array. The incident radiation may have phase information that canbe used by lock-in amplifiers, an optical modulator through whichscintillation light passes, or similar to reduce signal noise. Analysiscircuitry can include a computer, algorithms to correct for edge effectsand the like, noise reducing circuitry, and the like.

An optical coupling material, such as a liquid, gel, grease, polymer, orthe like, can be provided between components so as to reduce scatteringfrom refractive index discontinuities. For example, an optical couplingmaterial can be provided between sensors and a window (or crystal, if nowindow is used) to cut down light losses.

Applications

Applications include gamma ray cameras, and other radiation detectorsand imaging devices, such as nuclear medical devices. Applicationsinclude positron emission tomography (PET), single photon emissioncomputed tomography (SPECT), combined PET/SPECT, x-ray imaging, UVimaging, cosmic ray detection, and other imaging and detectionapplications.

The improved radiation detection efficiency, compared with provision ofuniform grooves across an entire light emitting face, is advantageousfor all applications, particularly where sensitivity is an issue (suchas combined PET/SPECT devices).

The methods and apparatus described herein may also be adapted to otherapplications, such as reducing edge effects in other materials, such aslenses, fluorescent materials, light emitting materials, light guidingmaterials (such as light pipes) and the like. Other examples arediscussed in more detail below.

General Removal of Edge Effects from Optical Elements

Approaches described herein can be used generally to remove edge effectsfrom optical elements. For example, a lens may be provided with one ormore grooves around the periphery of one or both surfaces of the lens.Grooves (the term is used generally to refer to any light guide) mayalso be provided around the peripheral edges of corneal implants,spectacle lenses, and other lenses and/or lens arrays. For example, in aspectacle application, one or more grooves could be partially orcompletely covered by a frame element.

A lasing material may be provided with one or more grooves in theperipheral region of the light emitting face of the laser material. Thismay be used to reduce stray light emerging from the laser material.

Grooves may also be provided in the peripheral regions of other opticalcomponents and systems, such as along the peripheral region ofwaveguides, or other components of integrated optical systems. Forexample, they may help reduce edge effects within a waveguide.

Hence, an example improved radiation detector includes a scintillator,the scintillator having a light-emitting face, a radiation receivingface, and a periphery between the light-emitting face and the radiationreceiving face, the periphery including an edge having an edgethickness. The scintillator emits scintillation light from the lightemitting face in response to radiation incident on the radiationreceiving face. The scintillator has a peripheral region proximate tothe edge, the scintillator including one or more light guides formedonly within the peripheral region. This is in contrast to other designswhere light guides are formed uniformly across the surface of thescintillator. The peripheral region can be a region within approximatelythree to eight times the edge thickness from the edge, or within adistance approximately equal to a sensor spacing or sensor diameter ifan array of sensors is used, or within half a sensor diameter (or sensorspacing). The area of the peripheral region can be less than the area ofa non-peripheral region (such as a central region) not proximate to theedge. The light guide provides an internal reflection or redirection ofscintillation light within the scintillator, before the scintillationemerges from the light emitting face.

If the radiation detector comprises a scintillator, a window, and anarray of sensors, each sensor in optical communication with the lightemitting face of the scintillator through the window, the light sensorshaving a light sensor diameter, the scintillator or the window can beprovided with one or more grooves formed in one or both faces thereof,the one or more grooves being formed within a distance less than a lightsensor diameter from an edge thereof.

The invention is not restricted to the illustrative examples describedabove. Examples are not intended as limitations on the scope of theinvention. Methods, apparatus, compositions, and the like describedherein are exemplary and not intended as limitations on the scope of theinvention. Changes therein and other uses will occur to those skilled inthe art. The scope of the invention is defined by the scope of theclaims. Subheadings in the specification are provided for convenienceonly. Examples, alternatives, and the like should be sought within theentire specification.

Patents or publications mentioned in this specification are incorporatedherein by reference to the same extent as if each individual publicationwas specifically and individually indicated to be incorporated byreference. In particular, U.S. Prov. Pat. App. Ser. No. 60/523,765 filedNov. 20, 2003, is incorporated herein in its entirety. Additionalinformation concerning imaging systems can be found in Applicant'sissued patents U.S. Pat. Nos. 6,525,320; 6.525,321; and 6,504,157; andPub. App. No. 2003/0136912, the entire content of all of which areincorporated herein by reference.

1. A radiation detector comprising: a continuous body of scintillationmaterial, the body-having a light-emitting face, a radiation receivingface, and a perimeter extending between the light-emitting face and theradiation receiving face, the perimeter including an edge, the edgehaving an edge thickness; the body of scintillation material emittingscintillation light from the light emitting face in response toradiation incident on the radiation receiving face; the body ofscintillation material having a peripheral region proximate to the edgeand a non-peripheral region spaced from the edge; and the body ofscintillation material including a plurality of spaced apart lightguides formed in the peripheral region and in the non-peripheral region,each of the light guides being operable to redirect a portion ofscintillation light before the portion of scintillation light emergesfrom the light emitting face; wherein each of the light guides has adepth, the depth of each light guide in the peripheral region beinggreater than the depth of the light guides in the non-peripheral region.2. The radiation detector of claim 1, wherein the depth of the lightguides is inversely correlated with the distance of the light guide fromthe edge.
 3. The radiation detector of claim 2, wherein the inversecorrelation is a linear correlation.
 4. The radiation detector of claim1, wherein at least two of the light guides in the non-peripheral regionhaving the same depth.
 5. The radiation detector of claim 4, whereineach of the light guides in the non-peripheral region have the samedepth.
 6. The radiation detector of claim 1, further comprising aplurality of light sensors, the sensors receiving scintillation light,the sensors each having a sensor diameter, the peripheral region being aregion within a distance approximately equal to a sensor diameter fromthe edge.
 7. The radiation detector of claim 1, wherein thenon-peripheral region is larger than the peripheral region.
 8. Theradiation detector of claim 1, wherein the peripheral region lies withina distance approximately equal to eight times the edge thickness fromthe edge.
 9. The radiation detector of claim 1, wherein the light guidescomprise grooves formed in the light emitting face or the radiationreceiving face.
 10. The radiation detector of claim 1, wherein the lightguides comprise reflecting films.
 11. The radiation detector of claim 1,wherein the light guides each comprise an interface between two regionsof different refractive indices.
 12. The radiation detector of claim 1,wherein each light guide provides an internal reflection ofscintillation light within the body of scintillation material.
 13. Theradiation detector of claim 1, wherein the light guides are eachsubstantially parallel to the edge.
 14. The radiation detector of claim1, wherein each of the light guides is disposed generally in a planedefined perpendicular to one of the faces of the body.
 15. The radiationdetector of claim 1, wherein the perimeter includes a first pair ofopposed edges and a second pair of opposed edges each extending betweenthe first pair of edges, the peripheral region including regionsadjacent each of the first pair of edges.
 16. The radiation detector ofclaim 1, wherein the plurality of spaced apart light guides aregenerally evenly spaced.
 17. The radiation detector of claim 1, whereinsome of the plurality of light guides extend from the light-emittingface part way to the radiation receiving face.
 18. The radiationdetector of claim 1, wherein some of the plurality of light guidesextend from the radiation receiving face part way to the light-emittingface.
 19. The radiation detector of claim 1, further comprising a windowdisposed adjacent the light-emitting face of the body of scintillationmaterial, the window being formed of a material substantiallytransparent to scintillation light, the window having at least one lightguide formed therein.
 20. The radiation detector of claim 1, furthercomprising an optical transmission element disposed adjacent theradiation receiving face of the body of scintillation material, theoptical transmission element having at least one light guide formedtherein.
 21. The radiation detector of claim 1, wherein the perimeterincludes a first pair of opposed edges and a second pair of opposededges each extending between the first pair of edges, the peripheralregion including regions adjacent each of the first pair of edges. 22.The radiation detector of claim 21, wherein the body of scintillationmaterial is generally rectangular and the edges are each generallystraight edges.
 23. The radiation detector of claim 21, wherein the bodyof scintillation material is generally curved, the first pair of opposededges being parallel generally straight edges and the second pair ofopposed edges being curved edges.
 24. A radiation detector, comprising:a scintillator producing scintillation light in response to incidentradiation, the scintillator having a radiation receiving face, and alight emitting face, and a perimeter edge; an array of sensors, eachsensor in optical communication with the light emitting face of thescintillator, each light sensor having a light sensor diameter; a windowbetween the scintillator and the array of light sensors, the windowhaving a first face, and a second face, and a perimeter edge; aperimeter region being defined adjacent the perimeter edges of thescintillator and window and a central region being defined inboard ofthe perimeter region; the scintillator or the window having a pluralityof grooves formed in one face thereof, the grooves each having a depthand being formed in the perimeter region and in the central region, thedepth of the grooves in the perimeter region being greater than thedepth of the grooves in the central region
 25. A method of treating anoptical material so as to modify the effect of internal edgereflections, the optical material having a face bounded by a perimeter,the perimeter including an edge, the method comprising: forming aplurality of grooves spaced apart across the face, each of the grooveshaving a depth; the face having a peripheral region proximate to theedge and a non-peripheral region spaced from the edge; the depth of thegrooves in the peripheral region being greater than the depth of thegrooves in the non-peripheral region.
 26. The method of claim 25,wherein the grooves are formed by cutting the optical material.
 27. Themethod of claim 25, wherein the optical material is a scintillator.